The inefficiency of incisions of ecteinascidin 743–DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent
Published Online: 2001-11-?
Journal: Chemistry & Biology•Publisher: Elsevier BV
Authors: David Bearss•Harold Kohn•Laurence H Hurley•Maha Zewail-Foote•Mary Guzman•Ven-Shun Li