Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
Published Online: 2021-03-?
Journal: The Lancet•Publisher: Elsevier BV
Authors: Aabidah Ali•Aadil Turabi•Aakifah Bibi Arif Sayed•Abdessamad Tahiri-Alaoui•Adam Berg•Adam Bird•Adam Finn•Adam J Ritchie•Adam J. Ritchie•Adam Lloyd•Adam Shea•Adam Truby•Adrian V S Hill•Adriana Tomic•Ahmed M. Salman•Aidan T. Hanrath•Aileen Burn•Airanuédida S. Soares•Alane Izu•Alasdair Munro•Alastair McGregor•Alberto San Francisco Ramos•Alessandra R. Souza•Alex Richter•Alexander Batten•Alexander D Douglas•Alexander J. Mentzer•Alexander J. Robbins•Alexander Richards•Alexander W. Tarr•Alexandra J. Spencer•Alexandre V Schwarzbold•Alice Bridges-Webb•Alice Lelliott•Aline Linder•Alisgair Esmail•Alison J. West•Alison M. Lawrie•Alka Ishwarbhai•Alvaro Edson Ramos Lessa•Alvaro Goyanna•Amada Sanchez-Gonzalez•Amanda Leach•Amar Joshi•Amber Thompson•Ameeka Thompson•Amelia M. Lias•Amina Goondiwala•Amisha Desai•Amy Beveridge•Amy Boyd•Amy Flaxman•Amy L. Ross Russell•Amy Shepherd•Ana Carolina F. Mesquita•Ana Cavey•Ana Luiza Perez•Ana Pittella•Ana V A Mendes•Andrea M Collins•Andrea Mazzella•Andreas Themistocleous•Andrew Alcock•Andrew Carson-Stevens•Andrew Duncan•Andrew J Pollard•Andrew Moultrie•Andrew S. Barr•Andrew Smith•Andrew T. Worth•Andrés Noé•Andy Yao•Angela Hyder-Wright•Angela M Minassian•Angela Oosthuizen•Angela Webster•Anil Pooran•Anishka Gunawardene•Ankush Khurana•Ann Sturdy•Anna Bara•Anna Calvert•Anna L Goodman•Anna Pennington•Anna Szigeti•Annabel Killen•Annette D. Samson•Annina B. Schmid•Anthonet Koen•Antonio Carlos da Silva Moraes•Anusha Nana•Arabella Stuart•Arnab Kar•Asad E. Bhorat•Asha Thombrayil•Aylin Oommen-Jose•Baktash Khozoee•Bassam Hallis•Beatriz Arns•Benjamin R. Underwood•Beth White•Betty Lebogang Tsheko•Bhavya Tyagi•Bhumika Patel•Birgit Hartnell•Blanche Oguti•Bongani Ndlovu•Bonolo Tladinyane•Brad E. Damratoski•Brama Hanumunthadu•Branwen Ellison-Handley•Brenda V.B. Paiva•Brian Angus•Bridget Watkins•Bruno Pereira Pereira Stuchi•Bruno S.D.F. Souza•Byron Rees•Caitlin L. Blundell•Carina C D Joe•Carina Jones•Carla Ferreira Da Silva•Carla Solórzano•Carmen Briner•Carol Taoushanis•Caroline Saunders•Caroline White•Catarina Oliveira•Catherine A. Cosgrove•Catherine Bailey•Catherine C. Smith•Catherine F. Houlihan•Catherine Hill•Catherine Hyams•Catherine M Green•Cecilia Njenga•Celia Mitton•Chandrabali Datta•Chanice Chanice•Charlie Brown-O'Sullivan•Charlotte Downing•Charlotte Sabine•Charlotte Trinham•Cheryl Turner•Christina Dold•Christina J. Cunningham•Christine Rollier•Christopher A Green•Christopher J A Duncan•Christopher J Williams•Christopher Jones•Christopher Myerscough•Christopher P. Conlon•Ciaran Gilbride•Cinthia M.C.D.L. Souza•Clair Harris•Claire Brown•Claire Docksey•Claire Huson•Claire Powers•Clare L Cutland•Clare Megson•Claudia Sala Andrade•Claudio Di Maso•Colin W. Larkworthy•Cristhiane Higa•Cushla Cooper•Daan Bormans•Daisy Harrison•Dalila Zizi•Dan Cullen•Daniel C. Smith•Daniel Hammersley•Daniel J Phillips•Daniel Jenkin•Daniel Knott•Daniel Marinho da Costa•Daniel O'Connor•Daniel Owens•Daniela M Ferreira•Danieli Bandeira•Daniella Berzenyi•Danielle Woods•Danny Wright•David A. Price•David B. Hettle•David Chapman•David Dearlove•David J. Smith•David Kerr•David O. Mainwaring•David P J Turner•David Pulido•David R.J. Owen•David Rea•Dearbhla M. Kelly•Debbie Barker•Debbie Kelly•Debora R.M.F. Cunha•Dennis Verbart•Diana M. Kluczna•Dimitra Pipini•Dipak Patel•Donal T. Skelly•Duncan Bellamy•Durga Rajapaska•Edna M.F. Palhares•Edson Makambwa•Eduardo A.M.S. Júnior•Eduardo Sprinz•Edward H. Arbe-Barnes•Ekaterina Watson•Ekta Mukhopadhyay•Eleanor Barnes•Eleanor Berrie•Elena Boland•Eleni Nastouli•Elissavet Nikolaou•Elizabeth A Clutterbuck•Elizabeth Clark•Elizabeth Hamilton•Elizabeth Howe•Elizabeth J. Davis•Elizabeth J. Kelly•Elizabeth J. Penn•Elizabeth Jones•Elizabeth R. Allen•Elizea Horne•Ella Morey•Ella Schofield•Else Margreet Bijker•Emilia Reyes Pabon•Emily A. Lees•Emily Beales•Emily Brunt•Emily Chiplin•Emma Bolam•Emma C Thomson•Emma Francis•Emma Marlow•Emma Plested•Emma Sheehan•Erica M. Lazarus•Erika Pachecho Dos Santos•Erika Santos•Eva Galiza•Eveline P Milan•Fabio Santos Amorim•Faeeza Kana•Faeezah Patel•Farah Shiham•Fawziyah Thompson•Fay L. Nugent•Federica Cappuccini•Felipe B. Alvernaz•Fernanda Barroso Costa•Fernando B. Presa•Fernando Ramos Lopez•Fiona C. Cuthbertson•Fiona Moghaddas•Foteini Andritsou•Franca Morselli•Frances Edwards•Francesca Bowring•Francesca Knapper•Francesca R. Donnellan•Frederic Jackson•Gabriela N. Marques•Gabrielle Novaes•Gail Lang•Garry Mallett•Gaurav Gupta•Gaurav Kwatra•Gavin Babbage•Gavin D. Barlow•Gavin R. Screaton•Gbadebo Adewatan•Gemma Walker•George M. Warimwe•Gerlynn Ferreras Tiongson•Gerry Trillana•Gertraud Morshead•Giacomo Gorini•Gina Hodges•Gordon MacGregor•Guilherme L. Sorio•Gurpreet Birch•Gurudutt Naik•Géssika Lanzillo A. Nunes•Hannah Davies•Hannah R. Sharpe•Hannah Roberts•Hannah Robinson•Hardeep Gill•Harriet Garlant•Hayley Colton•Hazel Fofie•Hazel Morrison•Heather Bletchly•Helen C Hill•Helen Jeffers•Helen R. Casey•Helen Ratcliffe•Helen Sanders•Helena C. Noal•Helena M. R.T. Parracho•Henry Fok•Holly E. Humphries•Holly E. Smith•Hosea Matlebjane•Hugh McCaughan•Ian Head•Ian Hirsch•Ian Poulton•Iason Vichos•Imam Shaik•Iman Satti•Imogen Stamford•Ina Schim van der Loeff•Inderjeet Bharaj•Indra Rudiansyah•Ingrid Cabrera Puig•Ioana Baleanu•Iona Jennifer Taylor•Irina Chelysheva•Isabela G.S. Gonzalez•Isabelle Silva Queiroz Oliveira•Jack E. Saunders•Jack Goodall•Jade Keen•Jade Rand•Jaisi Sinha•James Fletcher•James P. Adamson•James Perring•James Towner•Jamie Burbage•Jamie Fowler•Janet Grab•Jasmin Kinch•Jayne Goodwin•Jeanette H. Wells•Jeanne De Jager•Jee-Sun Cho•Jennifer Hill•Jennifer Phillips•Jennifer Pooley•Jeremy Aboagye•Jessica Barrett•Jessica C. Sale•Jessica Morgana Pinheiro•Jessica P.J. Larwood•Jessica Welch•Jilly Muller•Jim Chadwick•Jo Piper•Joan Du Plessis•Joanna McGlashan•Joanne McEwan•Johan Vekemans•Johann Greffrath•Johanna Kellett Wright•John Aaron Henry•John Davis•John Frater•John Haughney•Jonathan Bell•Jonathan C. MacDonald•Jonathan Drake•Jonathan Humphreys•Jordan R. Barrett•Joseph Hamlyn•José A.M. de Carvalho•José Cerbino-Neto•João R. Cardoso•Judith Davies•Julia A. Tree•Julia L. Marshall•Julia Thompson•Julian C. Knight•Julie Furze•Justin Green•Justin Taylor•Kajal Radia•Karen Bisnauthsing•Karen J. Ford•Karen Parsons•Karen R. Buttigieg•Karishma Gokani•Karyna A. Gibbons•Kate Templeton•Katerina S. Cheliotis•Katherine Gordon-Quayle•Katherine R W Emary•Katherine Sanders•Katherine Sharrocks•Kathryn Birchall•Kathryn Jones•Katie J Ewer•Katie O'Brien•Katrina Cathie•Katrina Hurley•Katrina M Pollock•Kedidimetse Matshidiso•Keertan Dheda•Keja Taylor•Kelly Barrett•Kelly Davies•Kelly Thomas•Kenneth F. Baker•Kerry Godwin•Kevin R. Bewley•Kevin Thompson•Kgaogelo Molapo•Khatija Ahmed•Kim Ryalls•Kim Sorley•Kirsten Beadon•Kirsty Adams•Kleber Giovanni Luz•Konstantinos Karampatsas•Konstantinos Liatsikos•Kush Naker•Kushal Mansatta•Kushala W.M. Abeyskera•Laiana Arruda•Lara Gracie•Larissa H.S. Thotusi•Larissa P. da Silva•Laura Bermejo•Laura Silva-Reyes•Laura Walker•Lauren Allen•Laís Y.M. Hayano•Leandro Bonecker Lora•Lee Fairlie•Leonardo Ramos•Liaquat Khan•Lidiana B. T.D. Silveira•Liliana Cifuentes•Lily Y Weckx•Linda Kay•Lindie Rossouw•Lis Moreno De Oliveira Kalid•Lisa Berry•Lisa Loew•Lisa Stockdale•Lisa V. Stockwell•Lizzie Stafford•Lloyd D.W. King•Lorena De Almeida Azi•Lorinda Pickup•Lorna McInroy•Louisa Rose•Louise Bates•Louise H. Strickland•Louise Spoors•Lucia Carratala Castro•Luciana Sowole•Lucy Kingham•Luiz Fernando F. Cezar•Luiza Assad•Luke Blackwell•Lydia Owen•Lygia Accioly Tinoco•Lynelle Mottay•Lynne Cornelissen•M Estée Török•Macarena Hermosin Herrera•Madita Gavrila•Maheshi N Ramasamy•Maia Patrick-Smith•Mainga Hamaluba•Malika Davids•Mandy Edwards•Mapule Moloi•Marcella A.S. Barbosa•Marcelo R. Primeira•Marco Polo Peralta Alvarez•Marcus Rex English•Maria Luisa Freire Gonçalves•Maria Moore•Maria T.D.C. Dantas•Mariana B.V. Silveira•Marianna Rocha Jorge•Marianne G. Oliveira•Marije K. Verheul•Marilia M. Franco•Marilúcia S.M. Freire•Marina Bauer Zambrano•Marion E.E. Watson•Marisa M. Groenewald•Marites Aban•Marivic Ricamara•Mark Hackett•Mark P. Ariaans•Mark Toshner•Mark Woodyer•Marni Moran•Marta Ulaszewska•Mary Kgomotso Phohu•Mary Plank•Marzena Wroblewska•Masebole Masenya•Matilda Lang•Matthew Adam•Matthew Clark•Matthew D Snape•Matthew E. Wand•Mayara F.S. Santos Guerra•Mduduzi Masilela•Meera Madhavan•Megan Baker•Mehreen S. Datoo•Melanie Bull•Melanie Carr•Melanie Greenland•Merin Thomas•Merryn Voysey•Michael J. Elmore•Michelangelo Cao•Michele Tomasicchio•Michelle Fuskova•Mihaela Pacurar•Mila Resuello-Dauti•Miles W. Carroll•Milla Dias Sampaio•Mimi M. Hou•Moncy Mathew•Mookho Malahleha•Mushiya Mpelembue•Mustapha Bittaye•Mutjaba Farooq•Mwila Kasanyinga•Nana-Marie Lemm•Naomi Coombes•Naomi Douglas•Natalia Salvador•Natalie Baker•Natalie G Marchevsky•Natalina Sutton•Natasha Jesudason•Nathifa Moyo•Neginsadat Mirtorabi•Neil J. Oldfield•Neil Ritchie•Nelly Owino•Nguyen Tran•Nicholas Byard•Nicholas J.W. Easom•Nick J. Edwards•Nick Smith•Nicky McRobert•Nicola Borthwick•Nicola Greenwood•Nicola Howell•Nicola Manning•Nicola Turner•Nisha Singh•Olga Mazur•Oliver Chester•Olivia Bird•Omar M. El Muhanna•Pablo Galian-Rubio•Pamela C. Proud•Paola Cicconi•Parvinder K Aley•Patricia Miralhes•Patrick J Lillie•Patrick J. Tighe•Patrick Kinch•Paul Cashen•Paul Klenerman•Paul T. Heath•Paul Williams•Paula De Almeida Azi•Paula Marriott•Paula O'Reilly•Pedro H.A. Fraiman•Pedro M Folegatti•Pedro M. Lages•Penny Bradley•Peter J. O'Reilly•Peter Zuidewind•Philip Baker•Philippa Tubb•Phillip Brown•Philomena Mweu•Piper Osborne•Poppy Iveson•Pritesh Bodalia•Qasim E Bhorat•Rachael Drake-Brockman•Rachel Anslow•Rachel Blacow•Rachel Colin-Jones•Rachel Cooper•Rachel L. Williams•Rachel Tanner•Rachel Varughese•Rachel White•Rafael Leal Zimmer•Rajeka Lazarus•Rameswara R. Segireddy•Raquel Lopez Ramon•Rebecca Beckley•Rebecca K Sutherland•Rebecca Law•Rebecca Makinson•Rebecca Winslow•Rebecca te Water Naude•Renata N.Õ. Mendonça•Renato Furlan Filho•Reshma Kailath•Ria Rabara•Ricardo Stein•Richard Fisher•Richard Morter•Richard P Marshall•Richard P. Marshall•Richard Tarrant•Richard Turner•Rinn Song•Rita Cardona•Robert Shaw•Roberta Senger•Rose Trivett•Ross Fothergill•Ross Malamatsho•Rubeshan Perumal•Ruth Drury•Ruth O. Payne•Ryan E. Robinson•Róisín Morgans•Saajida Akhalwaya•Sabina Ikram•Sabrina Fudge•Sagida Bibi•Sahir Yusuf Petkar•Sally Felle•Samantha Field•Samantha H. Fry•Samiullah Seddiqi•Samual van Eck•Samuel Lipworth•Samuel Pollard•Samuel Provstgaard-Morys•Sandra Belij-Rammerstorfer•Sarah Birch•Sarah C Gilbert•Sarah C. Warren•Sarah Crosbie•Sarah E. Silk•Sarah Kelly•Sarah Kidd•Sarah L. Davies•Sarah L.K. Collins•Sarah Murphy•Sarah Rhead•Saul N Faust•Savviz Mehdipour•Scott Bruce•Sean C. Elias•Sean Connarty•Sergio de Jesus Jnr•Shabir A Madhi•Shameem Jaumdally•Shaun L Barnabas•Shauna K. Masters•Sheena Quaid•Sheila Morris•Sherman D Padayachee•Shuchang Liu•Shuo Feng•Sibekezelo Msomi•Sibusiso Mnyakeni•Silvia Willingham•Simon Kerridge•Simon Royal•Sinéad Plant•Sofiya Fedosyuk•Sonia Serrano•Sonja Pieterse•Sophia Hawkins•Sophie Davies•Sophie Pueschel•Sophie Roche•Spyridoula Marinou•Stanislava Koleva•Stefania Di Marco•Stephanie A. Harris•Stephanie Leung•Stephanie Lloyd•Stephannie Salvador•Stephen Saich•Steve McSwiggan•Stewart Webb•Sue Ann Costa Clemens•Sue Belton•Sue Charlton•Sunder Chita•Susan J. Morris•Susan Jackson•Susan Palmer•Susan Tonks•Susana Camara•Susanna J. Dunachie•Susannah R. Blundell•Susanne Hodgson•Susie Ferguson•Sutika Bhikha•Suzete N. Farias Da Guarda•Suzette Oelofse•Syed Adlou•Taiane A. Vieira•Takalani Maoko•Tanaraj Perinpanathan•Tanja Brenner•Tannyth Gomes Dos Santos•Tanya Dinesh•Tao Dong•Tara A. Harris-Wright•Tawassal Riaz•Teresa Lambe•Tesfaye Demissie•Thainá G. Dos Santos•Thais R.Y. Castro•Thamyres Souza Lopez•Theresa Wardell•Thomas B. King•Thomas C Darton•Thomas C. Hart•Thomas D. Harrison•Thomas White•Thurkka Rajeswaran•Tiffany Sosa-Rodriguez•Tom Rawlinson•Tommy Rampling•Tonia M. Thomas•Tony Cox•Tonya L Villafana•Tricia Philip•Tumena Corrah•Ursula Taylor•Vicky L Baillie•Victoria Olchawski•Vidyashankara Iyer•Vincenzo Libri•Viv Thornton-Jones•Vivien Price•Wendy E.M. 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